Article
MYC immunohistochemical and cytogenetic analysis are required for identification of clinically relevant aggressive B cell lymphoma subtypes.
Leukemia & lymphoma - 1 Jun 2018
Raess Philipp W, Moore Stephen R, Cascio Michael J, Dunlap Jennifer, Fan Guang, Gatter Ken, Olson Susan B, Braziel Rita M
Abstract excerpt
Accurate subclassification of aggressive B cell lymphomas (ABCLs) requires integration of morphologic, immunohistochemical (IHC), and cytogenetic information. Optimal strategies have not been well defined for diagnosis of high grade B cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBLwR) and double expressor lymphomas with MYC and BCL2 protein overexpression. One hundred and eighty seven ABCLs were...
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