Article
Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities.
Journal of neurochemistry - 1 Apr 2015
Zhen Juan, Antonio Tamara, Cheng Shu-Yuan, Ali Solav, Jones Kymry T, Reith Maarten E A
Abstract excerpt
Previous studies point to quaternary assembly of dopamine transporters (DATs) in oligomers. However, it is not clear whether the protomers function independently in the oligomer. Is each protomer an entirely separate unit that takes up dopamine and is inhibited by drugs known to block DAT functio...
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