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Article

Single nucleotide polymorphisms in immune response genes in acute Q fever cases with differences in self-reported symptoms.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 May 2015

Wielders C C H, Hackert V H, Schimmer B, Hodemaekers H M, de Klerk A, Hoebe C J P A, Schneeberger P M, van Duynhoven Y T H P, Janssen R

Abstract excerpt

Genes involved in human immune response are well recognized to influence the clinical course of infection. The association of host genetics with susceptibility to and severity of clinical symptoms in acute Q fever was investigated. Single nucleotide polymorphisms (SNPs) in the IFNG (rs2430561/rs1861493), STAT1 (rs1914408), and VDR (rs2228570) genes were determined in 85 patients from the 2007 Dutch acute Q fever...

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Share to Disease Outbreaks
Share to Genes, MHC Class II
Share to Interferon-gamma
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Share to Q Fever
Share to Receptors, Calcitriol
Share to Severity of Illness Index
Share to STAT1 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 25577174
DOI: 10.1007/s10096-014-2310-9
PMCID: PMC7088184

Genes

IFNG
STAT1
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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