Article
Pneumococcal pneumonia suppresses allergy development but preserves respiratory tolerance in mice.
Immunology letters - 1 Mar 2015
Hartmann Carolin, Behrendt Ann-Kathrin, Henken Stefanie, Wölbeling Florian, Maus Ulrich A, Hansen Gesine
Abstract excerpt
Colonization with Streptococcus pneumoniae (S. pneumoniae) is associated with an increased risk for recurrent wheeze and asthma. Killed S. pneumoniae showed some potential as an effective immunomodulatory therapy in a murine model of asthma. Murine studies demonstrated protection against allergic asthma by symbiotic bacteria via triggering regulatory T cell response: treatment with killed S. pneumoniae resulted...
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