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Article

pH-sensitive oncolytic adenovirus hybrid targeting acidic tumor microenvironment and angiogenesis.

Journal of controlled release : official journal of the Controlled Release Society - 10 May 2015

Choi Joung-Woo, Jung Soo-Jung, Kasala Dayananda, Hwang June Kyu, Hu Jun, Bae You Han, Yun Chae-Ok

Abstract excerpt

Although oncolytic adenoviruses (Ads) are an attractive option for cancer gene therapy, the intravenous administration of naked Ad still encounters unfavorable host responses, non-specific interactions, and heterogeneity in targeted cancer cells. To overcome these obstacles and achieve specific t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25575865
DOI: 10.1016/j.jconrel.2015.01.005
PMCID: PMC4419830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25575865-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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