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Formulation of Folate-conjugated, Doxorubicin-loaded Human Serum Albumin Nanoparticles for Promotion of Gene Expression Associated with Apoptosis in Renal Cell Carcinoma

2021-02-25

Abstract excerpt

In this study, we developed a new, efficient targeting and pH-responsive formulation using folate (FA)-conjugated human serum albumin (HSA) nanoparticles to deliver doxorubicin (DOX) drug to renal cell carcinoma. FA was conjugated to HSA, and DOX was loaded into obtained FA-HSA NP using the desolvation method. FA-HSA-DOX NPs were examined using zeta potential and (DLS) measurements, dynamic light scattering, scann...

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Identifiers and source

Literature Corpus work
d8a33668-fb2b-5a39-9e0a-b8abb4ea0228
DOI
10.21203/rs.3.rs-229350/v1
Open publication

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Formulation of Folate-conjugated, Doxorubicin-loaded Human Serum Albumin Nanoparticles for Promotion of Gene Expression Associated with Apoptosis in Renal Cell CarcinomaDOI 10.21203/rs.3.rs-229350/v1
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