Current Principles, Challenges, and New Metrics in pH-Responsive Drug Delivery Systems for Systemic Cancer Therapy

Abstract excerpt

The paradigm of drug delivery via nano- and microcarriers is one of the leading ideas that enable overcoming the limitations of traditional chemotherapy. The trend toward more complex drug carriers capable of multifunctionality is observed in the literature. To date, prospects of stimuli-responsive systems to control the cargo release in the lesion nidus are widely accepted. Both endogenous and exogenous stimuli a...

Topics

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• ATP Synthase and ATPases Research
• Drug Delivery Systems
• Drug Design
• Drug Screening Assays, Antitumor
• Enzyme function and inhibition
• Hydrogen-Ion Concentration
• Metal complexes synthesis and properties
• Molecular Docking Simulation

Identifiers and source

Literature Corpus work

7e9ed71b-d090-5582-8569-d771f970b2be

DOI

10.20944/preprints202305.0289.v1