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Article

In silico analysis of nonsynonymous single nucleotide polymorphisms of the human adiponectin receptor 2 (ADIPOR2) gene.

Computational biology and chemistry - 1 Jun 2017

Solayman Md, Saleh Md Abu, Paul Sudip, Khalil Md Ibrahim, Gan Siew Hua

Abstract excerpt

Polymorphisms of the ADIPOR2 gene are frequently linked to a higher risk of developing diseases including obesity, type 2 diabetes and cardiovascular diseases. Though mutations of the ADIPOR2 gene are detrimental, there is a lack of comprehensive in silico analyses of the functional and structural impacts at the protein level. Considering the involvement of ADIPOR2 in glucose uptake and fatty acid oxidation, an...

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PMID: 28359874
DOI: 10.1016/j.compbiolchem.2017.03.005

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ADIPOR2

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