Article
Epigenetics and cardiovascular disease.
The Canadian journal of cardiology - 1 Jan 2013
Webster Andrew L H, Yan Matthew Shu-Ching, Marsden Philip A
Abstract excerpt
A commonly-assumed paradigm holds that the primary genetic determinant of cardiovascular disease resides within the DNA sequence of our genes. This paradigm can be challenged. For example, how do sequence changes in the non-coding region of the genome influence phenotype? Why are all diseases not shared between identical twins? Part of the answer lies in the fact that the environment or exogenous stimuli clearly...
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