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Article

The Tumor Suppressor BCL7B Functions in the Wnt Signaling Pathway.

PLoS genetics - 1 Jan 2015

Uehara Tomoko, Kage-Nakadai Eriko, Yoshina Sawako, Imae Rieko, Mitani Shohei

Abstract excerpt

Human BCL7 gene family consists of BCL7A, BCL7B, and BCL7C. A number of clinical studies have reported that BCL7 family is involved in cancer incidence, progression, and development. Among them, BCL7B, located on chromosome 7q11.23, is one of the deleted genes in patients with Williams-Beuren syndrome. Although several studies have suggested that malignant diseases occurring in patients with Williams-Beuren...

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Identifiers

PMID: 25569233
DOI: 10.1371/journal.pgen.1004921
PMCID: PMC4287490

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