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Article

Adaptive evolution of signaling partners.

Molecular biology and evolution - 1 Apr 2015

Urano Daisuke, Dong Taoran, Bennetzen Jeffrey L, Jones Alan M

Abstract excerpt

Proteins that interact coevolve their structures. When mutation disrupts the interaction, compensation by the partner occurs to restore interaction otherwise counterselection occurs. We show in this study how a destabilizing mutation in one protein is compensated by a stabilizing mutation in its...

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Identifiers

PMID: 25568345
DOI: 10.1093/molbev/msu404
PMCID: PMC4379405

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25568345-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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