Article
[Correlation between IDH1 mutation and prognosis in supratentorial high-grade astrocytomas].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Mar 2013
Xie Fei, Tang Jun-Jia, Wang Xiang, Liu Yan-Hui, Mao Qing
Abstract excerpt
OBJECTIVE: To study the correlation between isoeitratedehydrogenasel 1 (IDH1) mutation and prognosis in supratentorial high-grade astrocytomas. METHODS: There were 217 samples of supratentorial high-grade astrocytomas specimens collected for DNA extraction, IDH1 mutation of each patient was determined by PCR and direct sequencing. The differences of clinical features were compared between mutant group and wild...
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