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Article

Parental history of depression or anxiety and the cortisol awakening response.

The British journal of psychiatry : the journal of mental science - 1 Sept 2010

Vreeburg Sophie A, Hartman Catharina A, Hoogendijk Witte J G, van Dyck Richard, Zitman Frans G, Ormel Johan, Penninx Brenda W J H

Abstract excerpt

BACKGROUND: It is unclear whether altered hypothalamic-pituitary-adrenal (HPA) axis regulation, which frequently accompanies depression and anxiety disorders, represents a trait rather than a state factor. AIMS: To examine whether HPA axis dysregulation represents a biological vulnerability for these disorders, we compared cortisol levels in unaffected people with and without a parental history of depressive or...

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Source

Identifiers

PMID: 20807961
DOI: 10.1192/bjp.bp.109.076869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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