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Article

Structure of Neuroblastoma Suppressor of Tumorigenicity 1 (NBL1)

6 Jan 2015

Abstract excerpt

Bone morphogenetic proteins (BMPs) are antagonized through the action of numerous extracellular protein antagonists, including members from the differential screening-selected gene aberrative in neuroblastoma (DAN) family. In vivo, misregulation of the balance between BMP signaling and DAN inhibition can lead to numerous disease states, including cancer, kidney nephropathy, and pulmonary arterial hypertension....

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PMID: 25561725
DOI: 10.1074/jbc.m114.628412

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