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Article

One-stage vs. chromogenic assays in haemophilia A.

European journal of haematology - 1 Feb 2015

Potgieter Joachim J, Damgaard Michael, Hillarp Andreas

Abstract excerpt

Haemophilia A severity is closely correlated to the factor VIII (FVIII) activity, which can be measured in different ways. The original one-stage clotting assay is still the most widely used. The two-stage coagulation assay eliminated many of the drawbacks of the one-stage assay and was further developed into the chromogenic assay, a two-staged test with purified coagulation factors in the first stage, and a...

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PMID: 25560793
DOI: 10.1111/ejh.12500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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