Article
Haemophilia A and von Willebrand's disease.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jul 2010
Goodeve A C, Rosén S, Verbruggen B
Abstract excerpt
SUMMARY: Deficient or defective coagulation factor VIII (FVIII) and von Willebrand factor (VWF) can cause bleeding through congenital deficiency or acquired inhibitory antibodies. Recent studies on type 1 von Willebrand's disease (VWD), the most common form of the disease, have begun to explain its pathogenesis. Missense mutations of varying penetrance throughout VWF are the predominant mutation type. Other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.