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Article

The role of genetic variation across IL-1β, IL-2, IL-6, and BDNF in antipsychotic-induced weight gain.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jan 2015

Fonseka Trehani M, Tiwari Arun K, Gonçalves Vanessa F, Lieberman Jeffrey A, Meltzer Herbert Y, Goldstein Benjamin I, Kennedy James L, Kennedy Sidney H, Müller Daniel J

Abstract excerpt

OBJECTIVES: Antipsychotics with high weight gain-inducing propensities influence the expression of immune and neurotrophin genes, which have been independently related to obesity indices. Thus, we investigated whether variants in the genes encoding interleukin (IL)-1β, IL-2, and IL-6 and brain-derived neurotrophic factor (BDNF) Val66Met are associated with antipsychotic-induced weight gain (AIWG). METHODS:...

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Identifiers

PMID: 25560300
DOI: 10.3109/15622975.2014.984631

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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