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Article

The role of brain-derived neurotrophic factor (BDNF) gene variants in antipsychotic response and antipsychotic-induced weight gain.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Oct 2012

Zai Gwyneth C M, Zai Clement C H, Chowdhury Nabilah I, Tiwari Arun K, Souza Renan P, Lieberman Jeffrey A, Meltzer Herbert Y, Potkin Steven G, Müller Daniel J, Kennedy James L

Abstract excerpt

BACKGROUND: Brain-derived neurotrophic factor (BDNF) has extensive effects on the nervous system including cell survival, differentiation, neuronal growth and maintenance, as well as cell death. Moreover, it promotes synaptic plasticity and interacts with dopaminergic and serotonergic neurons, suggesting an important role on the alteration of brain function with antipsychotic medications and induced weight gain...

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Identifiers

PMID: 22642961
DOI: 10.1016/j.pnpbp.2012.05.014

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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