Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of extended passaging on the phenotype and osteogenic potential of human umbilical cord mesenchymal stem cells.

Molecular and cellular biochemistry - 1 Mar 2015

Shi Zhe, Zhao Liang, Qiu Gengtao, He Ruixuan, Detamore Michael S

Abstract excerpt

Retaining biological characteristics in the extended passaging is crucial for human umbilical cord mesenchymal stem cells (hUCMSCs) in tissue engineering. We aimed to assess morphology, viability, MSC marker expression, and osteogenic activity of hUCSMCs after extended passaging. Passages 4 (P4) and 16 (P16) hUCMSCs displayed similar morphology and viability. The flow cytometry results showed that CD73, CD90, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Cell Culture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Cell Survival

Share to Mesenchymal Stem Cells

Share to Osteogenesis

Share to Tissue Engineering

Share to Umbilical Cord

Source

Identifiers

PMID: 25555467
DOI: 10.1007/s11010-014-2303-0

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of extended passaging on the phenotype and osteogenic potential of human umbilical cord mesenchymal stem cells.PMID 25555467Read ↗

Human mesenchymal stem cells isolated from the umbilical cordSemantic proximity Read ↗

Fetal mesenchymal stem cells derived from human umbilical cord sustain primitive characteristics during extensive expansion.Semantic proximity Read ↗

Obtaining Human Umbilical Cord-Derived Mesenchymal Stem Cells and Cell Line Characterization: Immunophenotype, Multipotency and Cytogenetic StabilitySemantic proximity Read ↗

Expansion of human umbilical cord derived mesenchymal stem cells in regenerative medicineSemantic proximity Read ↗

Isolation and comparative analysis of potential stem/progenitor cells from different regions of human umbilical cordSemantic proximity Read ↗

Effects of Serial Passage on the Characteristics and Chondrogenic Differentiation of Canine Umbilical Cord Matrix Derived Mesenchymal Stem CellsSemantic proximity Read ↗

Characterization of human adipose-derived stem cells cultured in autologous serum after subsequent passaging and long term cryopreservation.Semantic proximity Read ↗

Changes in phenotype and differentiation potential of human mesenchymal stem cells aging in vitro.Semantic proximity Read ↗

Phenotypic changes associated with continuous long term in vitro expansion of bone marrow-derived mesenchymal stem cells.Semantic proximity Read ↗

Changes in the expression of CD106, osteogenic genes, and transcription factors involved in the osteogenic differentiation of human bone marrow mesenchymal stem cells.Semantic proximity Read ↗

The potential role of integrin alpha 6 in human mesenchymal stem cellsSemantic proximity Read ↗

Hyaluronan keeps mesenchymal stem cells quiescent and maintains the differentiation potential over timeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.