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Article

Insulinlike Growth Factor-1 and Its Binding Protein-3 Polymorphisms Predict Circulating IGF-1 Level and Appendicular Skeletal Muscle Mass in Chinese Elderly.

Journal of the American Medical Directors Association - 1 May 2015

Yang Chuan-Wei, Li Tsai-Chung, Li Chia-Ing, Liu Chiu-Shong, Lin Chih-Hsueh, Lin Wen-Yuan, Lin Cheng-Chieh

Abstract excerpt

BACKGROUND: Previous studies have demonstrated the polymorphisms of insulinlike growth factor-1 (IGF-1) and its binding protein-3 (IGFBP3) genes could affect the circulating IGF-1 level. Moreover, the serum IGF-1 level was correlated with muscle size. OBJECTIVES: This study aimed to explore the effect of polymorphisms of IGF1, IGFBP3, and IGFBP5 genes on appendicular skeletal muscle mass in Taiwanese older adults...

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Source

Identifiers

PMID: 25548030
DOI: 10.1016/j.jamda.2014.11.015

Genes

IGFBP3
IGF1
IGFBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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