Article
Interactions among IGF-1, AKT2, FOXO1, and FOXO3 variations and between genes and physical activities on physical performance in community-dwelling elders.
PloS one - 1 Jan 2020
Li Tsai-Chung, Wu Ching-Wei, Li Chia-Ing, Wu Fang-Yang, Liao Li-Na, Liu Chiu-Shong, Lin Chih-Hsueh, Wang Mu-Cyun, Yang Chuan-Wei, Lin Cheng-Chieh
Abstract excerpt
This study assessed the interactions among IGF-1, AKT2, FOXO1, and FOXO3 variations and the interactions of gene and physical activity on handgrip strength, arm muscle mass-adjusted handgrip (armGrip), gait speed (GS), timed up and go (TUG), and leg press strength (LPS). Nine single nucleotide polymorphisms (SNPs) containing three IGF-1 SNPs (rs6214, rs5742692, and rs35767), two AKT2 SNPs (rs892119 and...
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