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Article

Novel chromosomally encoded multidrug efflux transporter MdeA in Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Mar 2004

Huang Jianzhong, O'Toole Paul W, Shen Wei, Amrine-Madsen Heather, Jiang Xinhe, Lobo Neethan, Palmer Leslie M, Voelker LeRoy, Fan Frank, Gwynn Michael N, McDevitt Damien

Abstract excerpt

Antibiotic efflux is an important mechanism of resistance in pathogenic bacteria. Here we describe the identification and characterization of a novel chromosomally encoded multidrug resistance efflux protein in Staphylococcus aureus, MdeA (multidrug efflux A). MdeA was identified from screening an S. aureus open reading frame expression library for resistance to antibiotic compounds. When overexpressed, MdeA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14982783
DOI: 10.1128/AAC.48.3.909-917.2004
PMCID: PMC353085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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