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Article

Mining CK2 in Cancer

26 Dec 2014

Abstract excerpt

Cancer is a leading cause of death worldwide. Cancer cells proliferate uncontrollably and, many cases, spread to other parts of the body. A protein historically involved in cancer is protein kinase CK2. CK2 is a serine-threonine kinase that has been involved in cell growth, cell proliferation and cell apoptosis. CK2 functions as an oncogene when overexpressed in mouse tissues, and can synergize with known...

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PMID: 25541719
DOI: 10.1371/journal.pone.0115609

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