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Article

Impact of MMP-3 and TIMP-3 gene polymorphisms on prostate cancer susceptibility in North Indian cohort.

Gene - 10 Nov 2013

Srivastava Priyanka, Kapoor Rakesh, Mittal Rama Devi

Abstract excerpt

PURPOSE: Matrix metalloproteinases (MMPs) have been implicated in progression and metastases of different tumors. The balance between the MMPs and their natural inhibitors (tissue inhibitors of matrix metalloproteinases; TIMP) seem to be an important factor related to its role. The purpose of this study was to evaluate polymorphisms in the MMP-3 and TIMP-3 genes for their associations with prostate cancer (PCa)...

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PMID: 23872201
DOI: 10.1016/j.gene.2013.06.087

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