Article
A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae.
Molecular microbiology - 1 Apr 2015
Parsons Joshua B, Frank Matthew W, Eleveld Marc J, Schalkwijk Joost, Broussard Tyler C, de Jonge Marien I, Rock Charles O
Abstract excerpt
PlsX is an acyl-acyl carrier protein (ACP):phosphate transacylase that interconverts the two acyl donors in Gram-positive bacterial phospholipid synthesis. The deletion of plsX in Staphylococcus aureus results in a requirement for both exogenous fatty acids and de novo type II fatty acid biosynthesis. Deletion of plsX (SP0037) in Streptococcus pneumoniae did not result in an auxotrophic phenotype. The ΔplsX...
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