Article
Adaptation of Pseudomonas aeruginosa to various conditions includes tRNA-dependent formation of alanyl-phosphatidylglycerol.
Molecular microbiology - 1 Feb 2009
Klein Stefanie, Lorenzo Carlos, Hoffmann Sonja, Walther Johannes M, Storbeck Sonja, Piekarski Tanja, Tindall Bryan J, Wray Victor, Nimtz Manfred, Moser Jürgen
Abstract excerpt
The opportunistic bacterium Pseudomonas aeruginosa synthesizes significant amounts of an additional phospholipid, identified as 2' alanyl-phosphatidylglycerol (A-PG), when exposed to acidic growth conditions. At pH 5.3 A-PG contributed up to 6% to the overall lipid content of the bacterium. Sequence analysis of P. aeruginosa revealed open reading frame PA0920 showing 34% sequence identity to a protein from...
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