Article
Intergenerational anticipation of disease onset in people with multiple autoimmune syndrome.
Diabetes research and clinical practice - 1 Nov 2011
Giardino Giuliana, Aloj Giuseppina, Cirillo Emilia, Capalbo Donatella, Maio Filomena, Salerno Mariacarolina, Franzese Adriana, Pignata Claudio
Abstract excerpt
We compared the intergenerational variations of the clinical phenotype between 30 patients affected with multiple autoimmune syndrome (MAS) and their affected first- and second-degree relatives. Mean age at onset was always significantly higher in the previous generation than in probands for all the considered diseases.
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