Article
SNPs in APOBEC3 cytosine deaminases and their association with Visna/Maedi disease progression.
Veterinary immunology and immunopathology - 15 Feb 2015
Esparza-Baquer A, Larruskain A, Mateo-Abad M, Minguijón E, Juste R A, Benavides J, Pérez V, Jugo B M
Abstract excerpt
The Apolipoprotein B mRNA-editing catalytic polypeptide-like 3 (APOBEC3) genes are able to inhibit the replication of a wide range of exogenous retroviruses, as well as endogenous retroviruses and retrotransposons. Three APOBEC3 genes, named APOBEC3Z1, APOBEC3Z2 and APOBEC3Z3, have been described in sheep. In this work the three genes have been screened in order to identify polymorphisms. No polymorphism was...
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