Article
Revealing editing and SNPs of microRNAs in colon tissues by analyzing high-throughput sequencing profiles of small RNAs.
BMC genomics - 1 Jan 2014
Zheng Yun, Li Ting, Ren Ren, Shi Donghua, Wang Shengpeng
Abstract excerpt
BACKGROUND: Editing and mutations in microRNAs (miRNAs) can change the stability of pre-miRNAs and/or complementarities between miRNAs and their targets. Small RNA (sRNA) high-throughput sequencing (HTS) profiles contain miRNAs that are originated from mutated DNAs or are edited during their biogenesis procedures. It is largely unknown whether miRNAs are edited in colon tissues since existing studies mainly...
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