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Article

Donor ABCB1 genetic polymorphisms influence epithelial-to-mesenchyme transition in tacrolimus-treated kidney recipients.

Pharmacogenomics - 1 Dec 2014

Bloch Julie, Hazzan Marc, Van der Hauwaert Cynthia, Buob David, Savary Grégoire, Hertig Alexandre, Gnemmi Viviane, Frimat Marie, Perrais Michaël, Copin Marie-Christine, Broly Franck, Noël Christian, Pottier Nicolas, Cauffiez Christelle, Glowacki François

Abstract excerpt

AIM: The contribution of epithelial-mesenchymal transition (EMT) has been suggested in renal transplant recipients receiving calcineurin inhibitors and developing nephrotoxicity. MATERIALS & METHODS: We assessed whether interindividual variability in tacrolimus pharmacokinetics is associated with the occurrence in tubular cells of two EMT markers (vimentin, β-catenin) detected at 3-month in 140 allograft...

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to Cytochrome P-450 CYP3A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25521359
DOI: 10.2217/pgs.14.146

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Donor ABCB1 genetic polymorphisms influence epithelial-to-mesenchyme transition in tacrolimus-treated kidney recipients.PMID 25521359Read ↗

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