Article
Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor. Japan Marrow Donor Program.
The New England journal of medicine - 22 Oct 1998
Sasazuki T, Juji T, Morishima Y, Kinukawa N, Kashiwabara H, Inoko H, Yoshida T, Kimura A, Akaza T, Kamikawaji N, Kodera Y, Takaku F
Abstract excerpt
BACKGROUND: The requirements with respect to HLA compatibility and the relative importance of matching for individual class I and class II HLA alleles in the transplantation of hematopoietic stem cells from unrelated donors have not yet been established. METHODS: We performed retrospective DNA typing of alleles at 11 polymorphic loci of HLA genes in 440 recipients of hematopoietic stem cells from unrelated donors...
Topics
- Adolescent
- Adult
- Alleles
- Child
- Child, Preschool
- Female
- Genes, MHC Class I
- Graft vs Host Disease
- Hematopoietic Stem Cell Transplantation
- Histocompatibility Antigens Class I
