Visualization of astrocytic primary cilia in the mouse brain by immunofluorescent analysis using the cilia marker Arl13b.

Abstract excerpt

In vertebrates, almost all somatic cells extend a single immotile cilium, referred to as a primary cilium. Increasing evidence suggests that primary cilia serve as cellular antennae in many types of tissues by sensing chemical or mechanical stimuli in the milieu surrounding the cells. In rodents an antibody to adenylyl cyclase 3 (AC3) has been widely used to label the primary cilia of neurons in vivo by...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cerebrospinal fluid and hydrocephalus
• Share to Fetal and Pediatric Neurological Disorders
• Share to Genetic and Kidney Cyst Diseases