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Article

Genetic variants in nitric oxide synthase genes and the risk of male infertility in a Chinese population: a case-control study.

PloS one - 1 Jan 2014

Yan Lifeng, Guo Wenhui, Wu Shengmin, Liu Jining, Zhang Shenghu, Shi Lili, Ji Guixiang, Gu Aihua

Abstract excerpt

BACKGROUND: In recent years, oxidative stress has been studied extensively as a main contributing factor to male infertility. Nitric Oxide, a highly reactive free radical gas, is potentially detrimental to sperm function and sperm DNA integrity at high levels. Thus, the aim of this study was to investigate the associations between five polymorphisms in nitric oxide synthase genes (NOSs) and the risk of male...

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Source

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Identifiers

PMID: 25517965
DOI: 10.1371/journal.pone.0115190
PMCID: PMC4269448

Genes

NOS3
NOS1
NOS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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