Article
Impact of oxidative stress SNPs on sperm DNA damage and male infertility in a south-east Iranian population.
Reproduction, fertility, and development - 1 May 2022
Karam Zahra Miri, Baba Salari Milad, Anjom Shoaa Ahmad, Dehghan Kouhestani Somaye, Bahram Nejad Asma, Ashourzadeh Sareh, Zangouyee Moahammad Reza, Bazrafshani Mohammad Reza
Abstract excerpt
AIM: We examined four single nucleotide polymorphisms in four antioxidant genes (PON1 , CAT , GPx1 and SOD2 ) in 100 infertility cases and 100 controls from an Iranian population-based case-control study to confirm the assumption that polymorphisms in oxidative stress genes increase the risk of sperm DNA damage and idiopathic male infertility. METHODS: Restriction fragment length polymorphism and tetra-primer...
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