Article
Antioxidant Genes Variants and Their Association with Sperm DNA Fragmentation.
Biochemical genetics - 1 Dec 2024
Sharif Fadel A, Ashour Mohammed J, Abuwarda Hadeer N, Ismail Soher, Salem Noor, Suleiman Raed, Hassouna Nora
Abstract excerpt
Semen possesses a variety of antioxidant defense mechanisms which protect sperm DNA from the damaging effects of oxidative stress. Correlation between antioxidant genes variants and sperm DNA fragmentation (SDF) level is not sufficiently studied. Therefore, we investigated the association between several single nucleotide polymorphisms (SNPs): CYP1A1 (rs1048943A > G), CYP4F2 (rs2108622G > A), NRF2...
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