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Article

A genetic variant in 12q13, a possible risk factor for bipolar disorder, is associated with depressive state, accounting for stressful life events.

PloS one - 1 Jan 2014

Shimasaki Ayu, Kondo Kenji, Saito Takeo, Esaki Kosei, Otsuka Yasuyo, Mano Keiko, Ikeda Masashi, Iwata Nakao

Abstract excerpt

Genome-wide association studies (GWASs) have identified a number of susceptibility genes for schizophrenia (SCZ) and bipolar disorder (BD). However, the identification of risk genes for major depressive disorder (MDD) has been unsuccessful because the etiology of MDD is more influenced by environ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25517604
DOI: 10.1371/journal.pone.0115135
PMCID: PMC4269417

Genes

DHH
BDNF
DBH
FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25517604-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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