Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Behavioral abnormalities in prion protein knockout mice and the potential relevance of PrP(C) for the cytoskeleton.

Prion - 1 Jan 2014

Schmitz Matthias, Zafar Saima, Silva Christopher J, Zerr Inga

Abstract excerpt

The cellular prion protein (PrP(C)) is a highly conserved protein, which is anchored to the outer surface of the plasma membrane. Even though its physiological function has already been investigated in different cell or mouse models where PrP(C) expression is either upregulated or depleted, its e...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Animal
Share to Crosses, Genetic
Share to Cytoskeleton

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurodegenerative Diseases

Share to Nocodazole

Share to Prions

Share to PrPC Proteins

Share to Tubulin

Source

Open in PubMed Open full text

Identifiers

PMID: 25517431
DOI: 10.4161/19336896.2014.983746
PMCID: PMC4601510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25517431-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Behavioral abnormalities in prion protein knockout mice and the potential relevance of PrP(C) for the cytoskeleton.PMID 25517431Read ↗

Deletion of the prion gene Prnp affects offensive aggression in mice.Semantic proximity Read ↗

Olfactory behavior and physiology are disrupted in prion protein knockout mice.Semantic proximity Read ↗

Prion Protein Deficiency Results in Synaptic, Neural Network and Behavioral AlterationsSemantic proximity Read ↗

Neuroprotective and neurotoxic signaling by the prion protein.Semantic proximity Read ↗

Prion protein and agingSemantic proximity Read ↗

Insights into the physiological function of cellular prion protein.Semantic proximity Read ↗

Prion gene paralogs are dispensable for early zebrafish development and have nonadditive roles in seizure susceptibility.Semantic proximity Read ↗

Prion neurotoxicity: insights from prion protein mutants.Semantic proximity Read ↗

An ancient conserved role for prion protein in learning and memorySemantic proximity Read ↗

Lack of prion protein expression results in a neuronal phenotype sensitive to stress.Semantic proximity Read ↗

PrPs: Proteins with a purpose: Lessons from the zebrafish.Semantic proximity Read ↗

Loss of functional prion protein: a role in prion disorders?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.