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Article

PrPs: Proteins with a purpose: Lessons from the zebrafish.

Prion - 1 Jan 2000

Málaga-Trillo Edward, Sempou Emily

Abstract excerpt

The best-known attribute of the prion protein (PrP) is its tendency to misfold into a rogue isoform. Much less understood is how this misfolded isoform causes deadly brain illnesses. Neurodegeneration in prion disease is often seen as a consequence of abnormal PrP function yet, amazingly little is known about the normal, physiological role of PrP. In particular, the absence of obvious phenotypes in PrP knockout...

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Identifiers

PMID: 19786844
DOI: 10.4161/pri.3.3.9651
PMCID: PMC2802776

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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