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Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patients

2 Nov 2022

Abstract excerpt

The central theme of this enterprise is to find common features, if any, displayed by genetically different antimony (Sb)-resistant viscerotropic Leishmania parasites to impart Sb resistance. In a limited number of clinical isolates (n = 3), we studied the breadth of variation in the following dimensions: (a) intracellular thiol content, (b) cell surface expression of glycan having N-acetyl-D-galactosaminyl...

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PMID: 36405965
DOI: 10.3389/fcimb.2022.1021464

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