Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decreased antimony uptake and overexpression of genes of thiol metabolism are associated with drug resistance in a canine isolate of Leishmania infantum

4 Jun 2016

Abstract excerpt

Visceral leishmaniasis (VL) caused by the protozoan parasite Leishmania infantum, is one of the most important zoonotic diseases affecting dogs and humans in the Mediterranean area. The presence of infected dogs as the main reservoir host of L. infantum is regarded as the most significant risk for potential human infection. We have studied the susceptibility profile to antimony and other anti-leishmania drugs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Research on Leishmaniasis Studies
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27317865
DOI: 10.1016/j.ijpddr.2016.04.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decreased antimony uptake and overexpression of genes of thiol metabolism are associated with drug resistance in a canine isolate of Leishmania infantumPMID 27317865Read ↗

Treatment of canine visceral leishmaniasis with Milteforan <sup>™</sup> induces <i>Leishmania infantum</i> resistance to miltefosine and amphotericin BSemantic proximity Read ↗

Antimony resistance and gene expression in Leishmania : spotlight on molecular and proteomic aspectsSemantic proximity Read ↗

Role of efflux pumps and intracellular thiols in natural antimony resistant isolates of Leishmania donovani.Semantic proximity Read ↗

Antimony resistance mechanism in genetically different clinical isolates of Indian Kala-azar patientsSemantic proximity Read ↗

Molecular characterization of the MRPA transporter and antimony uptake in four New World Leishmania spp. susceptible and resistant to antimonySemantic proximity Read ↗

Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs.Semantic proximity Read ↗

Direct quantitative PCR detects genetic biomarkers of antileishmanial drug resistance in clinical samples from dogs with leishmaniosisSemantic proximity Read ↗

Impact of Genetic Diversity and Genome Plasticity of Leishmania spp. in Treatment and the Search for Novel Chemotherapeutic Targets.Semantic proximity Read ↗

Epidemiological Insights: Unraveling Drug Resistance in Leishmania Species through Comprehensive StudiesSemantic proximity Read ↗

Unresponsiveness to meglumine antimoniate in anthroponotic cutaneous leishmaniasis field isolates: analysis of resistance biomarkers by gene expression profilingSemantic proximity Read ↗

Differential gene expression analysis in antimony-unresponsive Indian kala azar (visceral leishmaniasis) clinical isolates by DNA microarraySemantic proximity Read ↗

Role of Aquaglyceroporin (AQP1) Gene and Drug Uptake in Antimony-resistant Clinical Isolates of Leishmania donovaniSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.