Article
Comparison of whole-genome (13X) and capture (87X) resequencing methods for SNP and genotype callings.
Animal genetics - 1 Feb 2015
Roux P F, Marthey S, Djari A, Moroldo M, Esquerré D, Estellé J, Klopp C, Lagarrigue S, Demeure O
Abstract excerpt
The number of polymorphisms identified with next-generation sequencing approaches depends directly on the sequencing depth and therefore on the experimental cost. Although higher levels of depth ensure more sensitive and more specific SNP calls, economic constraints limit the increase of depth fo...
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