Article
Efficiency of different strategies to mitigate ascertainment bias when using SNP panels in diversity studies.
BMC genomics - 5 Jan 2018
Malomane Dorcus Kholofelo, Reimer Christian, Weigend Steffen, Weigend Annett, Sharifi Ahmad Reza, Simianer Henner
Abstract excerpt
BACKGROUND: Single nucleotide polymorphism (SNP) panels have been widely used to study genomic variations within and between populations. Methods of SNP discovery have been a matter of debate for their potential of introducing ascertainment bias, and genetic diversity results obtained from the SNP genotype data can be misleading. We used a total of 42 chicken populations where both individual genotyped array data...
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