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Article

DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer.

BMC cancer - 16 Dec 2014

Martinez-Useros Javier, Rodriguez-Remirez Maria, Borrero-Palacios Aurea, Moreno Irene, Cebrian Arancha, Gomez del Pulgar Teresa, del Puerto-Nevado Laura, Vega-Bravo Ricardo, Puime-Otin Alberto, Perez Nuria, Zazo Sandra, Senin Clara, Fernandez-Aceñero Maria J, Soengas Maria S, Rojo Federico, Garcia-Foncillas Jesus

Abstract excerpt

BACKGROUND: DEK is a transcription factor involved in stabilization of heterochromatin and cruciform structures. It plays an important role in development and progression of different types of cancer. This study aims to analyze the role of DEK in metastatic colorectal cancer. METHODS: Baseline DE...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25515240
DOI: 10.1186/1471-2407-14-965
PMCID: PMC4300837

Genes

DEK
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25515240-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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