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Article

Monitoring the genomic stability of in vitro cultured rat bone-marrow-derived mesenchymal stem cells

1 Dec 2009

Abstract excerpt

Bone-marrow-derived mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and differentiation into multiple cell types. Accumulating preclinical and clinical evidence indicates that MSCs are good candidates to use as cell therapy in many degenerative diseases. For MSC clinical applications, an adequate number of cells are necessary so an extensive expansion is required. However, spontaneous...

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PMID: 19957104
DOI: 10.1007/s10577-009-9090-6

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