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Article

Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway.

Cancer research - 1 Feb 2015

Van Mater David, Añó Leonor, Blum Jordan M, Webster Micah T, Huang WeiQiao, Williams Nerissa, Ma Yan, Cardona Diana M, Fan Chen-Ming, Kirsch David G

Abstract excerpt

Some patients with soft-tissue sarcoma (STS) report a history of injury at the site of their tumor. Although this phenomenon is widely reported, there are relatively few experimental systems that have directly assessed the role of injury in sarcoma formation. We recently described a mouse model o...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25503558
DOI: 10.1158/0008-5472.CAN-14-2527
PMCID: PMC4327867

Genes

HGF
STS
MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25503558-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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