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Article

Oxidized Low‐Density Lipoprotein Inhibits THP‐1‐Derived Macrophage Autophagy via TET2 Down‐regulation

12 Dec 2014

Abstract excerpt

Oxidized low-density lipoprotein (ox-LDL) is an independent risk factor of atherosclerosis. However, the mechanism underlying its pro-atherosclerosis roles has not yet been well explored. DNA demethylation modification, via DNA methyltransferases or ten-eleven-translocation (TET) family, is a crisis epigenetic regulation for various biological and pathological processes. This study aimed to investigate the...

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PMID: 25503193
DOI: 10.1007/s11745-014-3977-5

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