Article
Genetically predicted testosterone and electrocardiographic QT interval duration in Chinese: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study.
International journal of epidemiology - 1 Apr 2015
Zhao Jie, Jiang Chaoqiang, Lam Tai Hing, Liu Bin, Cheng Kar Keung, Xu Lin, Long Mei Jing, Zhang Weisen, Leung Gabriel M, Schooling C Mary
Abstract excerpt
BACKGROUND: QT interval prolongation, a predictor of cardiac arrhythmias, and elevated heart rate are associated with higher risk of cardiovascular mortality. Observationally testosterone is associated with shorter corrected QT interval and slower heart rate; however, the evidence is open to residual confounding and reverse causality. We examined the association of testosterone with electrocardiogram (ECG)...
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