Article
HOXA7 stimulates human hepatocellular carcinoma proliferation through cyclin E1/CDK2
11 Dec 2014
Abstract excerpt
HOX genes are transcription factors that control morphogenesis, organogenesis and differentiation. Increasing evidence suggests that HOX genes play a role in hepatocellular carcinoma (HCC) progression; however few studies have defined the functional roles and mechanisms of action. In the present study, we used siRNA and forced-expression in multiple cell lines to define the role of HOXA7 in the regulation of...
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