Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of let‑7c on the PI3K/Akt/FoxO signaling pathway in hepatocellular carcinoma

6 Dec 2020

Abstract excerpt

The early diagnosis and treatment of liver hepatocellular carcinoma (LIHC) remains a major challenge. Therefore, it is of great significance to strengthen basic research on LIHC in order to improve the prevention and treatment of the disease. Numerous studies have indicated that the PI3K/Akt and FoxO signaling pathways mediate proliferation, survival and migration during the development of LIHC. Therefore, they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Ferroptosis and cancer prognosis
Share to FOXO transcription factor regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33376529
DOI: 10.3892/ol.2020.12357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of let‑7c on the PI3K/Akt/FoxO signaling pathway in hepatocellular carcinomaPMID 33376529Read ↗

Effects of Let-7c on the Processing of Hepatitis B Virus Associated Liver DiseasesSemantic proximity Read ↗

TCF19 enhances cell proliferation in hepatocellular carcinoma by activating the ATK/FOXO1 signaling pathwaySemantic proximity Read ↗

CircRNA-mTOR Promotes Hepatocellular Carcinoma Progression and Lenvatinib Resistance via PSIP1/c-Myc Axis Nuclear Translocation and Partially through Increasing EGFR ExpressionSemantic proximity Read ↗

Role of microRNAs in the main molecular pathways of hepatocellular carcinomaSemantic proximity Read ↗

Construction of liver hepatocellular carcinoma-specific lncRNA-miRNA-mRNA network based on bioinformatics analysis.Semantic proximity Read ↗

Circ-IGF1R has pro-proliferative and anti-apoptotic effects in HCC by activating the PI3K/AKT pathwaySemantic proximity Read ↗

Effect of Lenvatinib treatment on the cell cycle and microRNA profile in hepatocellular carcinoma cellsSemantic proximity Read ↗

Long noncoding RNA HULC accelerates the growth of human liver cancer stem cells by upregulating CyclinD1 through miR675-PKM2 pathway via autophagySemantic proximity Read ↗

Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progressionSemantic proximity Read ↗

Metabolomics and integrated network pharmacology analysis reveal SNKAF decoction Suppresses Cell Proliferation and Induced Cell Apoptisis in Hepatocellular Carcinoma via PI3K/Akt/P53/FoxO Signaling AxisSemantic proximity Read ↗

Hepatocellular Carcinoma: Molecular Pathways and New Therapeutic TargetsSemantic proximity Read ↗

A comprehensive review and in silico analysis of the role of survivin (BIRC5) in hepatocellular carcinoma hallmarks: A step toward precisionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.