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Article

Polymorphism of the OLR1 3'UTR potential microRNA binding site and risk of Alzheimer's disease: a meta-analysis.

Genetics and molecular research : GMR - 4 Dec 2014

Kong Y, Wu J B, Wang X, Zhao J F, Song H, Yuan L D

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that contributes to dementia in the elderly population. Genome-wide linkage analysis has identified chromosome 12p as the AD-susceptible region, which includes lectin-like oxidized low-density lipoprotein receptor 1 (OLR1). The OLR1 +1073 C/T single-nucleotide polymorphism is located in the 3'-untranslated region of the gene and may influence...

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3' Untranslated Regions
Alzheimer Disease
Binding Sites
Case-Control Studies
Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Scavenger Receptors, Class E

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PMID: 25501227
DOI: 10.4238/2014.December.4.10

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OLR1

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